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Question: Name the layers of the cornea and their function.

Answer: You can actually devide the cornea into 5 layers, these include:

1. Epithelium Layer: This is the surface layer of cells. They provide barrier function and a smooth surface for the tear film.
2. Bowmans Layer: A tough layer of basement membrane right under the epithelium. This layer is tough, and keeps the cornea from swelling forward … which means when the cornea swells, it must do so backwards into the anterior chamber.
3. Stroma: composed of highly arranged collagen fibers and supporting keratocytes, the cornea stroma provides the majority of the cornea. Injuries at this level can scar.
4. Descemet’s Layer: An inner layer of basement membrane. This layer is important for the health of endothelial cells. One of the leading needs for cornea transplant is from a dystrophy of Descemet’s layer called Fuch’s dystrophy.
5. Endothelium: The Endothelium is a crucial layer as it works as a barrier and a pump that keeps the cornea from getting too wet.

Most of these layers are easy to remember: especially the epithelium, stroma, and endothelium. To help you remember the location of the other layers: remember that Descemet’s is Deep, while Bowman’s is up in the BellTower.



28 Comments



YOU HAVE A VERY MUCH IMPORTENT INFORMATION, THIS INFORMATION IS RELEVANT PLEASE KEEP THE STANDARD UP.



Comment by Bongeka Koto — April 7, 2009



Oh dear! It’s called the cornea, not retina!

Editors Note: Right you are! I’ve fixed that typo … Thanks for noticing!



Comment by Oops — May 7, 2009



just wanna ask my cornea is damage i have a blurry sight an optho clean it!! just wanna ask if cornea can heal itself!! il w8 ur ans in my email add ll10zai35ll@yahoo.com.ph thx



Comment by marc — August 10, 2009



dear, i required models or pictures of amino acids transporters in the cornea or in corneal layers..for teaching purposes can you provide me?



Comment by sachin — January 18, 2010



to remember…. EBCDE like ABCDE from the alphabet…for easily remembered…



Comment by Patchintero — January 30, 2010



remember ABCDE
A= sufcace epithelium
B= bowmans membrane



Comment by satish koirala — March 23, 2010



C= connective tissue Stroma
D= descemet’s membrane
E= endothelium………..



Comment by satish koirala — March 23, 2010



question- can bowmans layer regenerate if damaged?
thanks



Comment by john scott — February 28, 2011



IF THIS LAYER -BOWMANS LAYER- IS DAMAGED AS BY A SCRATCH OR CUT IT DOES NOT REGENERATE TO ITS ORIGINAL FORM AND THUS SCARRING OCCURS.



Comment by DR.SYL. EDO — June 12, 2011



thanks very much, you information has worked much for mylevel



Comment by loku simaya — September 1, 2011



how to measure iop in hazy and abraded cornea in cases of chemical burns



Comment by vaishali — November 5, 2011



just like ABCDE…



Comment by kinzang — December 1, 2011



A very nice doc for studying & teaching. Thanks v.m !!



Comment by demelash — December 27, 2011



iop measurement in hazy,abraded cornea by non-contact air-puff tonometer.



Comment by asad — December 29, 2011



Thanks



Comment by Dr Obechi — January 8, 2012



Very nice way of teaching..



Comment by madiha — August 27, 2012



Metabolically active layet of cornea?



Comment by sat — September 8, 2012



thank u….



Comment by elham — October 22, 2012



thnx keep the standard up



Comment by hitesh — December 6, 2012



It’s very informative…Thanks and God bless!



Comment by Jane M.L. — December 22, 2012



What are the regenerative layers of cornea..?



Comment by pravallika — March 7, 2013



endotheleum regenerative layer of cornea



Comment by sandy — March 12, 2013



Thnkz it’s vry nyc hav solved my problem



Comment by mrinali kachey — March 23, 2013



Is descement membrane regenerative



Comment by Kom — April 8, 2013



such a great site to learn easy



Comment by sana — June 17, 2013



There is another layer now known:
http://www.aaojournal.org/article/S0161-6420(13)00020-1/abstract
http://www.livescience.com/37348-new-layer-discovered-in-human-eye.html
One of the commenters on the second page claims the layer was known previously, but not named.



Comment by David Bump — August 30, 2013



David, I’ve heard of the new layer but have been waiting to hear from my corneal docs whether it truly matters. The nice thing about anatomy (as a field of study) is that it tends to advance slowly.

As to whether we should “name” this as a “layer” is debatable. You could probably name lots of areas/intersections in the body … but it may just complicate understanding if it has no relevance.

For the purposes of this book/question, I’m going to leave it at five layers for now. Thanks for commenting and the links.



Comment by Timothy Root, M.D. — August 30, 2013



nice information.thank you Doctors



Comment by kikoti — April 28, 2014




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